Why Ketamine for Anxiety?

Anxiety disorders are the most common mental health conditions in the U.S., affecting over 40 million adults. While benzodiazepines and SSRIs are first-line treatments, many patients either don't respond, experience intolerable side effects, or develop tolerance. Ketamine offers a fundamentally different approach through glutamate modulation.

• Rapid anxiolytic effects, often within hours of the first session
• Works through glutamate pathways, not serotonin or GABA
• No risk of benzodiazepine dependence or tolerance
• Can help generalized anxiety, social anxiety, and mixed anxiety-depression
• Promotes neural flexibility to break rigid anxiety patterns

How Ketamine Reduces Anxiety

Anxiety often involves hyperactive neural circuits—the brain's threat-detection system stuck in overdrive. Ketamine helps by promoting neuroplasticity, allowing the brain to form new, healthier patterns of thought and response. This "neural reset" can quiet overactive anxiety circuits.

• Modulates glutamate to reduce overactive threat responses
• Enhances BDNF to support healthier neural pathways
• Temporarily reduces default mode network (DMN) activity linked to rumination
• Creates a window of enhanced neuroplasticity for therapeutic change
• Paired with integration practices for lasting behavioral change

Who Is a Good Candidate?

Ketamine therapy may be appropriate for adults with anxiety disorders who haven't found adequate relief from conventional treatments.

• Adults 18+ with generalized anxiety disorder (GAD), social anxiety, or related conditions
• Tried at least one anxiety medication without adequate relief
• Experiencing significant functional impairment from anxiety
• No uncontrolled blood pressure or cardiovascular instability
• Willing to engage in integration and therapy alongside treatment

At-Home Treatment for Anxiety

Treating anxiety at home removes one of the biggest barriers—the anxiety of going to a clinic. Our telehealth model lets you receive treatment in your safest, most comfortable environment.

• No clinic visits—sessions in the comfort of your home
• AI companion (KetAI) provides gentle, calming guidance
• Therapeutic soundscapes designed for relaxation
• Pre-session preparation checklist to reduce anticipatory anxiety
• Post-session integration with breathwork and grounding exercises
• Ongoing physician support via secure telehealth